Data from the phase 3 study confirmed the lot consistency, immunogenicity, safety, and tolerability of a toxoid-based Clostridioides difficile vaccine. Neutralizing antibody responses 1 month after ...

Intestinal stem cells help regenerate the lining of the intestine, and that lining or epithelium plays a number of critical roles in digestion, nutrient absorption, and immunity. Scientists have now ...

BOSTON – Estimated to cause almost half a million infections per year, the bacterium Clostridioides difficile, also known as C. difficile or “C. diff,” can cause diarrhea and inflammation of the large ...

Clinical findings shed more light on toxins produced by C. diff A team from Nashville, Tenn.-based VanderbiltUniversityMedicalCenter has teased out new secrets from Clostridium difficile, the ...

The presence of antigen-specific and neutralizing antibodies was not associated with Clostridioides difficile infection symptoms, severity, therapy approach, treatment response, or recurrences in a ...

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Charles Darkoh, Ph.D., a researcher at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, was recently awarded a five-year, $1.9 million R01 grant by the ...

Clostridium difficile, a bacterium known to cause symptoms from diarrhea to life-threatening colon damage, is part of a growing epidemic for the elderly and hospitalized patients. Biologists have now ...

Isolating asymptomatic C. diff carriers linked with lower incidence of infection Screening and isolating asymptomatic Clostridium difficile carriers was associated with a reduction in incidence of ...

A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an ...