Life-saving medical treatments often come with heavy physiological costs that extend beyond the targeted organ or disease.

Depression continues to grip roughly 332 million people worldwide, according to World Health Organization estimates. While standard antidepressant medications offer relief for many, nearly half of ...

Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine ...

As a stimulant, caffeine and caffeinated drinks hold promise to help people fight off the natural slow down that descends during the winter months. Coffee can provide a cognitive boost, behavioral ...

If you feel that your morning coffee puts a spring in your step, science agrees. In the first large-scale real-world study of its kind, researchers have found that caffeine isn't just a stimulant but ...

Coffee and the caffeine in it can interact with some drugs. Learn more about which drugs you should not take with coffee and when to discuss it with a healthcare provider.

The coffee paradox in adenosine-mediated antidepressant action. Depression (left) and coffee consumption (right) are both linked through adenosine signaling (center), creating a pharmacological ...

When I finally confronted my dependency and gave up coffee three months ago, my body wasn’t happy. In the mornings during the time that I would normally have my espresso, my thoughts tried to bargain ...