Calcium-activated chloride channels (CaCCs) play a pivotal role in a myriad of physiological processes. By responding to intracellular calcium concentration, these channels regulate epithelial ...

Structure of the calcium-activated chloride channel TMEM16A. The channel, which consists of two identical subunits, is shown in the center. The position of the membrane is indicated by lines. The ion ...

It is vital to the regulation of cell activities through its role as a second messenger. Calcium signaling is the process whereby low cytoplasmic concentrations are deliberately increased to activate ...