Adult cells can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only. This limits the potential use of adult cells for therapy.

Mouse embryonic stem cells (ESCs) have emerged as ideal tools for developmental biology research due to their characteristics such as unlimited proliferation and pluripotent differentiation potential.

Totipotency is the ability of a cell to develop into individuals through elaborated processes of embryogenesis and is created during the development of the precursors of sperm and eggs, which are ...