DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off ...

(A) DNA methylation is maintained by DNMT1 on hemimethylated DNA after replication, while DNMT3A/3B catalyse de novo methylation on unmethylated DNA. In mammals, this modification is primarily found ...

Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single cells, an advance that will help researchers better study the role of ...

DNA methylation is a widely studied epigenetic modification with crucial roles in gene regulation, development, and disease, particularly in cancer. It has immense potential as a biomarker for early ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

DNA methylation profiles in whole blood samples from 77 patients with CN-AML in The Cancer Genome Atlas (LAML cohort) were analyzed. Individual 5’-cytosine-phosphate-guanine-3’ (CpG) sites were ...

Chronic diseases such as cardiovascular disease, cancer, and diabetes are driven by systemic inflammation, a natural biological response to harmful stimuli, injuries, or infections. C-reactive protein ...

In a recent study published in the journal Molecular Psychiatry, a team of researchers conducted a large-scale meta-analysis consisting of an epigenome-wide association study to understand whether ...