For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder. Early studies suggested promise, but enthusiasm faded after ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

Receptor chromatography has emerged as a pivotal tool in the modern bioanalytical and drug discovery landscape. By utilising immobilised receptors on a solid chromatography support, this technique ...

Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major ...

Researchers uncover a hidden nanoscale mechanism critical for Met receptor activation, providing a new blueprint for targeted ...

Although computational methods within drug discovery are well established, there is an indisputable gap when it comes to novel AI tools capable of rapidly, robustly and cost-effectively predicting the ...

Clinical Outcomes and Efficacy of Human Epidermal Growth Factor Receptor 2–Targeted Therapy in Breast Cancer With Uncommon In Situ Hybridization Patterns or Discordant Immunohistochemistry The ...

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major ...