Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

CAPTION: (Top) Condensins seem to act as a molecular crosslinkers to make loops. (Bottom, left) Condensins (red) locate around chromosome center. (Bottom, right) Nucleosomes around the periphery ...

An organism grows and repairs its body using a form of cell division known as mitosis. To divide, a cell must replicate the chromosomes, which carry the DNA (the instructions needed to build the body) ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early ...

Arteriovenous malformations, a hallmark of hereditary hemorrhagic telangiectasia, may be driven by endothelial cell-cycle acceleration via CDK6, suggesting potential for repurposing CDK6 inhibitors.

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

New research sheds light on embryonic mitosis, thanks to a combination of novel imaging techniques, CRISPR/Cas9 genome editing technology, a modern protein-knockdown system, and medaka, or Japanese ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early embryonic development have ...