Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Researchers have discovered that Alzheimer’s disease may be reversible in animal models through a treatment that restores the ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

Blood vessel changes in the eye mirror brain damage in mice with a gene variant linked to dementia, potentially offering ...

Mice are indispensable in biomedical research due to their genetic and anatomical similarities to humans, short lifespans, ...

The lack of animal models that mimic human disease impedes the study of many pathologies that still lack treatment beyond symptom relief. This is what has happened so far with PURA syndrome, a rare ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

After the DNA sequence of the boy’s genome showed a mutation in the VMA21 gene, one of the known causes of XMEA, University of Alabama at Birmingham and Children’s of Alabama pediatric neurologist ...

For more than a century, Alzheimer’s disease has been framed as irreversible. Once memory and thinking decline, recovery has ...