By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative enzyme switch called "Switchbody," which is activated when bound to its ...
The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...
Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...
Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...
DALLAS – July 19, 2002 – UT Southwestern Medical Center at Dallas researchers, using X-ray crystallography, have discovered how a particular cell enzyme finds its target and clearly carries out its ...
Cryo-EM reconstructions of the human ATR–ATRIP complex show how clinical small-molecule inhibitors like VE-822 and RP-3500 bind to and inhibit ATR activity. A research team led by Prof. Gang Cai and ...
New live-cell imaging data show that Telomir-1 markedly lowers intracellular iron levels at submicromolar concentrations in ...
Chondrocytes play a crucial role in skeletal development. Many bones, such as those in the arms and legs, are formed through ...
Researchers at Baylor College of Medicine and collaborating institutions report in the journal Nature Communications how a mutation in the enzyme SKD3 can cause a form of a genetic disease known as ...
A harmful and often deadly substance made by bacteria, a bacterial toxin manipulates host cell functions and disrupts vital cell processes in a living organism. Bacterial toxins hit host organisms ...
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