NFL Week 18 picks, score predictions for every game this week, including Lions-Bears, Chargers-Broncos, Colts-Texans, Ravens-Steelers, Seahawks-49ers.

SportsLine's model simulates every game 10,000 times and reveals its NFL picks today for spread, over/under and money line

NFL Week 18 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs near.

Some of the site's predictions differ from NFL Week 17 odds and other NFL Week 17 picks for NFL Week 17 games. How correct will the analytics be this week? Click on each game for more NFL Week 17 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

The NFL playoff picture will finalize after the NFL Week 18 schedule. The top seeds in both the AFC and NFC are still at stake, as is who is going to take the NFC South and AFC North title and the playoff spot that comes with it.

Office Pool – NFL Game Picks Our staff will pick the winner of every NFL contest every week. They will also rank their confidence level in their selection, ranging from 1 (least confident) to 16 (most confident). We'll also combine everyone's confidence points, giving you a Wisdom of the Staff confidence level as well.

The Athletic’s Mike Jones has been a fan of the work of both New England Patriots head coach Mike Vrabel and quarterback Drake Maye for much of the season. The national NFL writer tabbed Vrabel as his Coach of the Year pick at the midway point of the 2025 campaign and called Maye’s Patriots one

It's true the Titans secondary is occupied by practice squad players, but 13.5 points is a lot. I'm not calling for an upset, but don't forget that this Jaguars team has lost to the Titans in a critical Week 18 spot before.