Transfusion guidelines regarding platelet-count thresholds before the placement of a central venous catheter (CVC) offer conflicting recommendations because of a lack of good-quality evidence. The ...

THE variability in the natural history of both acquired and idiopathic aplastic anemia makes it difficult to evaluate the success of any specific program of therapy. With careful attention to ...

Cryopreserved platelets cost more and are linked to worse bleeding and clinical outcomes than liquid-stored platelets in a study of adults undergoing cardiac surgery.

Platelet transfusion thresholds in according bleeding risk and the presence of bleeding. WHO = World Health Organization. “In practice, we see all too often [that] prophylactic transfusion of ...

65.4% of hospitalized ITP inpatients did not have a bleeding episode or surgical procedure associated with their platelet transfusion. Platelet transfusions were not associated with improved clinical ...

ASCO convened an Expert Panel and conducted a systematic review of the medical literature published from September 1, 2014, through October 26, 2016. This review builds on two 2015 systematic reviews ...

Treatment of hairy-cell leukemia with cladribine: response, toxicity, and long-term follow-up. Seventy-eight patients undergoing induction therapy for acute leukemia were randomized to receive ...

Febrile responses to platelet transfusions are common but some can be life-threatening and the cause of these reactions is largely unknown. In June 23 Lancet, Richard Phipps and colleagues from ...

A preliminary study published in this week's issue of THE LANCET suggests a possible explanation for the biological process responsible for inducing fever and related symptoms after the transfusion of ...