Cytochrome c oxidase (COX) of the electron transport system is thought to be the rate-limiting step in cellular respiration and is found mutated in numerous human pathologies. Here, we employ ...

Membrane proteins are key components of living cells. They constitute one-third of the ORFs of virtually all genomes, perform crucial roles, and are targeted by a huge number of drugs. When present in ...

Proteins were evolved to perform specific functions within biological systems, such as catalyzing reactions and transporting small molecules or ions. This functionality necessitates a large degree of ...