JSTOR Daily

Patient Attitudes Toward the Use of Fecal Microbiota Transplantation in the Treatment of Recurrent Clostridium difficile Infection

Background. Fecal microbiota transplantation (FMT), a safe, effective alternative therapy for recurrent Clostridium difficile infection (CDI), is infrequently used, in part because of an assumption ...
JSTOR Daily

A Common Polymorphism in the Interleukin-8 Gene Promoter Is Associated with an Increased Risk for Recurrent Clostridium difficile Infection

Background. Neutrophil recruitment coordinated by intestinal interleukin (IL)-8 secretion is a key component in the pathogenesis of Clostridium difficile infection (CDI). We hypothesized that a common ...
Medscape

NICE Recommends Faecal Microbiota Transplant for Recurrent Clostridium Difficile Infections

The National Institute for Health and Care Excellence (NICE) has recommended faecal microbiota transplant (FMT) as a treatment option for those with recurrent Clostridium difficile (C diff) infections ...
Becker's ASC

Study: Fecal Microbiota Transplantation Effective Treatment of Recurrent Clostridium difficile

The procedure involves transplanting a stool sample from a healthy donor to treat C. difficile. One-quarter of patients who contract a C. difficile infection will have a recurrence, and those who do ...
Becker's Hospital Review

5 risk factors associated with recurrent C. diff. infections

Researchers may not yet understand the mechanism behind recurrent Clostridium difficile infections, but they may have isolated five risk factors, according to a study published in Infection Control & ...
Becker's Hospital Review

Single fecal transplant comparable to standard of care for treating recurrent C. diff

A single fecal transplantation is not more effective than the existing standard of care — administration of oral vancomycin taper — for treating patients with recurrent Clostridium difficile infection ...
Medscape

Fidaxomicin: A Novel Macrocyclic Antibiotic for the Treatment of Clostridium difficile Infection

Am J Health Syst Pharm. 2012;69(11):933-943. Based on current clinical trials reporting fewer recurrences among patients treated with fidaxomicin in which the non-NAP1/BI/027 strains were isolated, ...
EurekAlert!

Clostridium difficile infections linked to higher death rates if infection recurs

Vienna, Austria: Repeated infection with the bacterium Clostridium difficile (C. difficile), which causes stomach upsets and diarrhoea, is linked to higher death rates, as well as having a significant ...
Science Daily

Fecal microbe transplants: B. vulgatus genes that correlate with early colonization

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor ...
Nasdaq

Seres Therapeutics Announces Completion of Enrollment in SER-109 Phase 3 ECOSPOR III Study for Recurrent Clostridium difficile Infection and Provides Clinical Pipeline Updates

– Company assessing the impact of COVID-19 on SER-287, SER-401 and SER-301 clinical development programs – “We are pleased to have achieved this critically important corporate milestone. SER-109 has ...
EurekAlert!

Comparison of fecal transplant using capsule vs. colonoscopy to prevent Clostridium difficile infection

Why The Research Is Interesting: Clostridium difficile infection (CDI) causes inflammation of the colon and severe diarrhea. The infection occurs when normal gut bacteria are disrupted. Fecal ...
Business Wire

Artugen Therapeutics Announces First Patient Dosed with ART24, Artugen’s First Clinical Product Candidate for Prevention of Recurrence of Clostridium Difficile Infection

CONCORD, Mass. & DUBLIN, Ireland--(BUSINESS WIRE)--Artugen Therapeutics Limited, a Company developing novel live biotherapeutics (LBPs) for patients living with infectious, inflammatory and oncologic ...