Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...
Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...
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Repairing DNA Double-Strand Breaks May Improve Genomic Stability by Limiting Organelle-to-Nucleus Gene Transfer
A recent study in Nature Plants examined the genetic regulation of endosymbiotic gene transfer (EGT) in plants. Researchers found that deoxyribonucleic acid (DNA) double-strand break repair (DSBR) ...
Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...
The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...
Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases like skin cancer, cells also have repair mechanisms that can fix ...
Greenland sharks use a unique DNA repair process to protect their eyesight, revealing clues about longevity and retinal preservation.
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Francesca Storici, Georgia Institute of Technology (THE CONVERSATION) Your DNA is ...
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