Researchers report that SUMOylation of pseudorabies virus thymidine kinase at two lysine residues controls the enzyme's ...

Oct 12 (Reuters) - Bristol Myers Squibb said on Monday a lower dose of its experimental drug helped slow the decline in lung ...

In patients with gout and/or familial Mediterranean fever, colchicine-statin combination is tied to a higher risk for ...

Researchers in Adelaide and Singapore have uncovered new clues as to why some people with chronic myeloid leukemia (CML) ...

A pan-cancer computational study identified the buckwheat-derived compound fagopyrine as a strong predicted binder to the ...

By integrating single-molecule fluorescence imaging, AlphaFold structure prediction, and biochemical and cell-biological functional validation, the researchers found that the two double-stranded ...

Traditional kinase inhibitors face a trade-off between potency and selectivity because their affinity depends on limited molecular interactions in a single highly ...

Arvinas presented early biomarker data on ARV-102, an oral drug built to clear the LRRK2 protein, at a major Parkinson’s ...

You understand the importance of data utilization. However, you don't know where to start. You know there must be a vast ...

Proof of concept demonstrated for first-in-class oral therapy, addressing multiple aspects of atopic dermatitis pathology and with the potential ...

First clinical data for leniolisib in a larger group of PID participants beyond APDS, supporting the potential of targeted PI3Kδ inhibition to ...

New research links karyoptosis in Alzheimer’s disease to nuclear collapse, offering potential therapeutic targets to slow ...