Frontiers

Integrating single-cell RNA sequencing with spatial transcriptomics reveal the fibrosis-related genes in hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, with limited efficacy of current therapies in advanced cases. As a key risk factor for HCC, liver ...
Frontiers

Single-nucleus and Spatial Transcriptomics Reveal Intestinal Cellular Heterogeneity, Differentiation, and Cell Communication Mechanisms in SAP-induced Intestinal Injury

The final, formatted version of the article will be published soon. Abstract Background Acute pancreatitis (AP) is a severe inflammatory disease that frequently causes multi-organ damage, with ...
IEEE

Frequency-Aware Spatial-Temporal Attention Explainable Network for EEG Decoding

Abstract: Representation learning in spatial and temporal domains has shown significant potential in EEG decoding, advancing the field of brain-computer interfaces (BCIs). However, the critical role ...
IEEE

SpaNN: Spatial Transcriptomic Data Enhancement Using Deep Neural Network

Abstract: Spatial transcriptomic sequencing technology is a powerful tool that combines gene expression data with their physical locations in tissues or organs, providing researchers with ...